Pyridine, 2-bromo-3,5-difluoro-
2-Bromo-3,5-difluoropyridine
CAS: 660425-16-1
Molecular Formula: C5H2BrF2N
Pyridine, 2-bromo-3,5-difluoro- - Names and Identifiers
| Name | 2-Bromo-3,5-difluoropyridine |
| Synonyms | 2-Bromo-3,5-Fluoropyridine 2-Bromo-3,5-difluoropyridine Pyridine, 2-bromo-3,5-difluoro- |
| CAS | 660425-16-1 |
| InChI | InChI=1/C5H2BrF2N/c6-5-4(8)1-3(7)2-9-5/h1-2H |
Pyridine, 2-bromo-3,5-difluoro- - Physico-chemical Properties
| Molecular Formula | C5H2BrF2N |
| Molar Mass | 193.98 |
| Density | 1.808±0.06 g/cm3 (20 ºC 760 Torr) |
| Boling Point | 36-37°C/0.6mm |
| Flash Point | 44.0±25.9℃ |
| pKa | -4.05±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Pyridine, 2-bromo-3,5-difluoro- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| Hazard Class | IRRITANT |
Pyridine, 2-bromo-3,5-difluoro- - Introduction
2-Bromo-3,5-difluoropyridine is an organic compound with the chemical formula C5H2BrF2N. The following is a description of its nature, use, preparation and safety information:
Nature:
2-Bromo-3,5-difluoropyridine is a colorless liquid with a bitter taste. It has a melting point of -1.5°C and a boiling point of 89-96°C. It is less soluble in water and more soluble in organic solvents such as ether and methanol. It is not flammable, but it can decompose to produce harmful gases under open flame or high temperature.
Use:
2-Bromo-3,5-difluoropyridine is an important intermediate compound, which has a wide range of applications in pharmaceutical synthesis, pesticide synthesis and materials science. It can be used to synthesize various drugs and pesticides, such as anticancer drugs, insecticides and fungicides. In addition, it can also be used as a raw material for photoelectric materials, liquid crystal materials and dyes.
Preparation Method:
The preparation method of 2-Bromo-3,5-difluoropyridine is usually achieved by reacting 3,5-difluoropyridine with hydrogen bromide. The reaction requires the use of a suitable solvent and catalyst, such as sodium hydroxide or potassium carbonate.
Safety Information:
2-Bromo-3,5-difluoropyridine is a hazardous chemical, and it is necessary to pay attention to safe operation measures when using it. It can cause irritation and damage to the eyes, skin and respiratory system. During use or storage, contact with fire sources, high temperature and oxidizing agents should be avoided. Also, wear appropriate personal protective equipment such as lab gloves, goggles and protective clothing. Pay attention to comply with relevant laws and regulations during treatment, and dispose of wastes correctly to avoid environmental pollution. In the event of an accident, the necessary first aid measures should be taken immediately and medical assistance should be sought.
Nature:
2-Bromo-3,5-difluoropyridine is a colorless liquid with a bitter taste. It has a melting point of -1.5°C and a boiling point of 89-96°C. It is less soluble in water and more soluble in organic solvents such as ether and methanol. It is not flammable, but it can decompose to produce harmful gases under open flame or high temperature.
Use:
2-Bromo-3,5-difluoropyridine is an important intermediate compound, which has a wide range of applications in pharmaceutical synthesis, pesticide synthesis and materials science. It can be used to synthesize various drugs and pesticides, such as anticancer drugs, insecticides and fungicides. In addition, it can also be used as a raw material for photoelectric materials, liquid crystal materials and dyes.
Preparation Method:
The preparation method of 2-Bromo-3,5-difluoropyridine is usually achieved by reacting 3,5-difluoropyridine with hydrogen bromide. The reaction requires the use of a suitable solvent and catalyst, such as sodium hydroxide or potassium carbonate.
Safety Information:
2-Bromo-3,5-difluoropyridine is a hazardous chemical, and it is necessary to pay attention to safe operation measures when using it. It can cause irritation and damage to the eyes, skin and respiratory system. During use or storage, contact with fire sources, high temperature and oxidizing agents should be avoided. Also, wear appropriate personal protective equipment such as lab gloves, goggles and protective clothing. Pay attention to comply with relevant laws and regulations during treatment, and dispose of wastes correctly to avoid environmental pollution. In the event of an accident, the necessary first aid measures should be taken immediately and medical assistance should be sought.
Last Update：2024-04-09 21:11:58
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CAS: 660425-16-1
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CAS: 660425-16-1
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